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Metamizole sodium injection is our best-selling products. Description Metamizole sodium injection.

　The main ingredients of this product and its chemical name: This product is mainly composed of dipyrone, its chemical name [ ( 1,5 - dimethyl-2 - phenyl -3-2,3 - dihydro-1H- pyrazol -4 - yl) methyl ] amino] methane sulfonic acid sodium salt - hydrate.

　MF : C13H16N3NaO4S · H2O

　Properties: colorless or slightly yellow transparent liquid.

　Toxicology : The product compound aminopyrine and sodium sulfite combining soluble in water , antipyretic, and analgesic effects compared Aminopyrine fast and strong .

　Pharmacokinetics: injections rapidly effective , T1 / 2 of about 1 to 4 hours .

　Indications: fever heat when used , can also be used for headaches, migraines , muscle pain, joint pain and dysmenorrhea. This product also has a strong anti -rheumatic effect , can be used for acute rheumatoid arthritis. But because this product may cause serious adverse reactions , rarely used in rheumatic diseases .

　Dosage: deep intramuscular injection once a 0.25 ~ 0.5g; pediatric first 5 ~ 10mg/kg.

　Adverse reactions: The product stimulation of the gastrointestinal tract , although small, but can cause the following adverse reactions:

　① blood aspect , which can cause agranulocytosis , the occurrence rate of about 1.1% , acute onset, severe cases can be fatal , can also cause autoimmune hemolytic anemia, thrombocytopenic purpura , aplastic anemia ; ② skin aspects , can cause hives , exudative erythema and other allergic manifestations, can occur in severe exfoliative dermatitis, epidermolysis psychosis ; ③ local reactions at the injection site may have redness , pain, a few days later subsided ; some patients showed symptoms of sepsis , subcutaneous bleeding , pus or purple , often take several months to heal. ④ allergic rash or drug fever , urticaria, can have serious exfoliative dermatitis , epidermolysis bullosa disease leading to death. Individual cases of anaphylactic shock can occur , and even lead to death. ⑤ even when administered injections cause sweating, exhaustion symptoms occur .

　Contraindications: aminopyrine of the goods or have a history of allergies were banned.

　Note: ( 1 ) the product easier to cause adverse reactions , especially not with the injection, particularly disabled points in joints .

　( 2 ) those who are allergic to drugs ( such as ketones drugs pyrazolyl ) should not be used , the injection should not be mixed with any other drugs.

　( 3 ) This product should not be long term. Use a long time can cause neutropenia, thrombocytopenic purpura , severe aplastic anemia may have even lead to death.

　( 4 ) should be strictly controlled doses , an adult should not exceed 0.5g, children once to 8 ~ 10mg/kg appropriate.

　( 5 ) the infirm caution.